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ACRP Certified Professional : ACRP-CP

ACRP-CP Exam Simulator
  • Exam Code: ACRP-CP
  • Exam Name: ACRP Certified Professional Exam
  • Updated: Aug 17, 2026
  • Q & A: 127 Questions and Answers
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ACRP ACRP-CP Exam Syllabus Topics:

SectionWeightObjectives
Data Management and Informatics17%- Data collection
  • 1. Electronic data capture systems
  • 2. Case report form design and completion
- Data quality control
  • 1. Data validation and cleaning
  • 2. Query management and resolution
- Data reporting
  • 1. Data integrity and security
  • 2. Database lock and data transfer
Regulatory and Compliance Requirements17%- ICH Guidelines
  • 1. E9 Statistical Principles
  • 2. E6(R2)/E6(R3) Good Clinical Practice
  • 3. E11 Pediatric Trials
  • 4. E8 General Considerations for Clinical Trials
  • 5. E2A Expedited Reporting
- International standards
  • 1. Declaration of Helsinki
- Compliance procedures
  • 1. Regulatory submissions and approvals
  • 2. Audits and inspections
Study Design and Conduct17%- Study implementation
  • 1. Investigational product management
  • 2. Site selection and activation
  • 3. Study monitoring and oversight
- Study planning
  • 1. Study population and eligibility criteria
  • 2. Protocol development and amendments
  • 3. Sample size and statistical considerations
Professionalism and Ethical Practice15%- Professional standards
  • 1. Confidentiality and conflict of interest
  • 2. Role responsibilities and boundaries
- Continuous improvement
  • 1. Quality assurance and process improvement
  • 2. Professional development and education
Ethical and Participant Safety Considerations19%- Ethical principles
  • 1. Clinical equipoise and therapeutic misconception
  • 2. Human subject protections and privacy
- Clinical care and management of research participants
  • 1. Continuity of medical care
  • 2. Standard of care vs protocol requirements
  • 3. Informed consent development and review
- Safety monitoring and reporting
  • 1. Adverse event identification and classification
  • 2. Safety information evaluation and communication
Clinical Study Operations15%- Project management
  • 1. Timeline and budget management
  • 2. Vendor and stakeholder management
- Site management
  • 1. Study documentation and record keeping
  • 2. Site personnel training and delegation

ACRP Certified Professional Sample Questions:

1. A study protocol must contain which of the following elements?

A) Chemical structure of the IP
B) Data management plan
C) Participant reimbursement details
D) Description of statistical methods


2. The IB contains which of the following sections?

A) Participant eligibility criteria
B) Participant dosing schedule
C) IP preparation instructions
D) Known pharmacokinetic effects


3. Which document confirms the PI's agreement to permit auditing at the study site?

A) IB
B) Protocol
C) ICF
D) Delegation Log


4. A serious unexpected ADR is one:

A) Where the severity of the reaction is not consistent with IB.
B) Severity and nature of the reaction is consistent with protocol.
C) That results in the death of the subject.
D) That does not need to be reported to the IRB/IEC.


5. The IRB/IEC has decided to not approve a clinical trial. Who must they notify in writing?

A) PI
B) Regulatory Agency
C) CRC
D) Sponsor


Solutions:

Question # 1
Answer: D
Question # 2
Answer: D
Question # 3
Answer: C
Question # 4
Answer: A
Question # 5
Answer: A

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